Male Swiss mice (18–20g) were obtained from Butantan Institute (São Paulo, Brazil).
Animals were housed in a temperature-controlled room (22–24°C) with a 12h light-dark cycle and fresh water and food ad libitum.
However, the factors involved in foam cell formation induced by a GIIA s PLA2 are still unknown.
Here, we investigated the participation of lipid homeostasis-related factors in LD formation induced by MT-III in macrophages.
DMSO and BSA were obtained from Amresco (Solon, OH, USA).